Prescription pillsWhat is Clopidogrel?

Clopidogrel is an anti-platelet drug that works by decreasing the ability of platelets to stick together to form clots.


  • Decrease the risk for the development of blood clots in instances of feline cardiomyopathies, pulmonary hypertension, and other causes of increased clotting risk

Adverse Effects

[please contact CVCA should any of these symptoms be noted]

  • Drooling secondary to bitter taste (more common in cats)
  • Decreased appetite, vomiting or diarrhea most common side effects
  • Small increased risk for bleeding

Client Information

  • Best given with food to help with the taste and to avoid stomach
  • Available in tablets. Can be reformulated in chewables. Can be made into a liquid, however not recommended due to the bitter taste
  • Commonly used concurrently with aspirin
  • Does not require any specific monitoring
  • Please tell any veterinary professional that your pet is on Clopidogrel/Plavix, especially prior to any dental or surgical procedures

Interactions with Other Drugs

  • Increased risk for bleeding if used with aspirin, coumadin, or non-steroidal antiinflammatories (Rimadyl, Deramaxx, Metacam)
  • Omeprazole decreases efficacy
  • Increases blood levels of torsemide

Standard Dosage Forms

Clopidogrel 75mg tablets



Drug Handouts