Clopidogrel

What is Clopidogrel?

Clopidogrel is an anti-platelet drug that works by decreasing the ability of platelets to stick together to form clots.

Uses/Indications

• Decrease the risk for the development of blood clots in instances of feline cardiomyopathies, pulmonary hypertension, and other causes of increased clotting risk

Adverse Effects

[please contact CVCA should any of these symptoms be noted]

• Drooling secondary to bitter taste (more common in cats)
• Decreased appetite, vomiting or diarrhea most common side effects
• Small increased risk for bleeding

Client Information

• Best given with food to help with the taste and to avoid stomach
  upset
• Available in tablets. Can be reformulated in chewables. Can be made into a liquid, however not recommended due to the bitter taste
• Commonly used concurrently with aspirin
• Does not require any specific monitoring
• Please tell any veterinary professional that your pet is on Clopidogrel/Plavix, especially prior to any dental or surgical procedures

Interactions with Other Drugs

• Increased risk for bleeding if used with aspirin, coumadin, or non-steroidal antiinflammatories (Rimadyl, Deramaxx, Metacam)
• Omeprazole decreases efficacy
• Increases blood levels of torsemide

Standard Dosage Forms

Clopidogrel 75mg tablets

Synonyms

Plavix